No, in fact pain is very uncommon symptom of cancer. Whether a patient has pain may depend on the type of cancer, the extent of the disease, and the patient’s tolerance for pain. Most pain occurs when the cancer grows and presses against bones, organs, or nerves. Pain may also be a side effect of treatment. However, pain can generally be relieved or reduced with prescription medicines or over-the-counter drugs recommended by the doctor.
Microorganism | Related cancer |
Hepatitis B and Hepatitis C virus | Liver cancer |
Human Papilloma Virus (HPV) | Cervical cancer, Penile cancer, Head and Neck Cancers |
Human Immunodeficiency Virus (HIV) | Kaposi sarcoma, Ca cervix |
Helicobacter pylori | Stomach cancer |
Schistosomiasis | Bladder cancer |
Human T-lymphotropic virus Type I (HTLV-1) | T-cell leukemia and T-cell lymphoma |
Cancer is caused by changes in genes that normally control the growth and death of cells. Certain lifestyle and environmental factors can change some normal genes into genes that allow the growth of cancer. Many gene changes that lead to cancer are the result of tobacco use, diet, exposure to ultraviolet (UV) radiation from the sun, or exposure to carcinogens (cancer-causing substances) in the workplace or in the environment. Some gene alterations are inherited (from one or both parents). However, having an inherited gene alteration does not always mean that the person will develop cancer; it only means that the chance of getting cancer is increased. Scientists continue to examine the factors that may increase or decrease a person’s chance of developing cancer.
However, in 70% of breast cancer patients no risk factors can be identified.
Regular consumption of excessively spicy diet, chillies, eating very hot food or drinking hot tea/coffee, excessive intake of fried food, eating dried or smoked fish, eating the food which contains preservatives, artificial flavouring agents, colouring agents, eating excessive fatty food are known to increase the risk of cancer.
Yes, alcohol is classified as a carcinogen by the International Agency for Research on Cancer. Consumption of alcohol increases the risk of numerous cancers, including those of the liver, esophagus, pharynx, oral cavity, larynx, breast, colon and rectum in a dose-dependent fashion. Evidence is convincing that excessive alcohol consumption increases the risk of primary liver cancer, probably through cirrhosis and alcoholic hepatitis. About 75% of cancers of the esophagus, pharynx, oral cavity, and larynx are attributable to alcohol and tobacco, with a marked increase in risk among drinkers who also smoke, suggesting a multiplicative effect. Mechanisms may include direct damage to the cells in the upper gastrointestinal tract, modulation of DNA methylation, which affects susceptibility to DNA mutations, and an increase in acetaldehyde, the main metabolite of alcohol, which enhances proliferation of epithelial cells, forms DNA adducts, and is a recognized carcinogen. The association between alcohol consumption and breast cancer is notable because a small but significant risk has been found even with one drink per day. Mechanisms may include an interaction with folate, an increase in endogenous estrogen levels, and elevation of acetaldehyde. Notably, for most cancer sites, no important difference in associations was found with the type of alcoholic beverage, suggesting a critical role of ethanol in carcinogenesis.
Yes, regular consumption of red meat has been associated with an increased risk of cancer; specially the colorectal cancer. The association is strongest for processed meat. Few studies have also underlined the association of red meat consumption and breast cancer (specially in pre-menopausal women). Mechanisms through which red meat may increase cancer risk include anabolic hormones routinely used in meat production, heterocyclic amines, and polycyclic aromatic hydrocarbons formed during cooking at high temperatures, the high amounts of heme iron, and nitrates and related compounds in smoked, salted, and some processed meats that can convert to carcinogenic nitrosamines in the colon.
The role of soy products has been considered for breast carcinogenesis. In Asian countries, which traditionally have a high consumption of soy foods, breast cancer rates have been low until recently. Soybeans contain isoflavones, phytoestrogens that compete with estrogen for the estrogen receptor. Hence, soy consumption may affect estrogen concentrations differently depending on the endogenous baseline level. This mechanism may also contribute to the equivocal results of studies on soy foods and breast cancer risk. Childhood intake of soy was more relevant to breast cancer prevention than adult consumption.
Faulty genes that run in some families may cause a small number of cancers. Cancer can be hereditary in 5% to 10% of cases. Cancers which may be hereditary are breast, ovary, colon, leukemias. A sign that cancer MAY be hereditary within family is when several members of the same side of a family have had the same type of cancer (e.g. they’ve all had breast cancer), especially if some have developed it at a younger than usual age.
Cancer may run in families even due to non-genetic factors. The family members may have exposure to common cancer causing factors like faulty dietary habits, addictions, common environmental factors, etc.
Yes, overweight and inactivity are major contributors to cancer risk. Various studies indicate that obese individuals have substantially higher mortality from all cancers and in particular from colorectal cancer, postmenopausal breast cancer, uterine cancer, cervical cancer, pancreatic cancer, and gall bladder cancer than their normal-weight counterparts. Adiposity and in particular waist circumference are predictors of colon cancer incidence among women and men. Weight gain of 10 kg or more is associated with a significant increase in postmenopausal breast cancer incidence among women who never used hormone replacement therapy, while weight loss of comparable magnitude after menopause substantially decreases breast cancer risk.
The mechanisms whereby adiposity increases risk of various cancers are probably multiple. Overweight is strongly associated with endogenous estrogen levels, which likely are related to the excess risks of endometrial and breast cancers. The reasons for the associations with other cancers are less clear, but excess body fat is also related to higher levels of insulin, lower levels of binding proteins for sex hormones and insulin-like growth factor 1(IFG-1), and higher levels of various inflammatory factors, all of which have been hypothesized to be related to risks of various cancers.
Summary of the Strength of Epidemiologic Evidence for Association between Physical Activity or Obesity and Cancer Risk, by Organ Site | ||
Physical Activity | Overweight/Obesity | |
Breast, postmenopausal | +++ | +++ |
Colon | +++ | +++ |
Endometrium | + | +++ |
Esophagus, adenocarcinoma | ? | +++ |
Kidney, renal cell carcinoma | ? | +++ |
Pancreas | ? | ++ |
Gallbladder | ? | ++ |
Non-Hodgkin’s lymphoma | ? | + |
Prostate, aggressive | ++ | + |
Lung | + | ? |
Ovary | ? | ? |
+++, evidence is convincing; ++, evidence is probable; +, evidence is possible; ?, evidence remains insufficient and inconclusive. |
Yes, chronic or long standing infection with some microorganisms (viruses, bacteria, protozoa) is known to cause cancer. For example:
Microorganism | Related cancer |
Hepatitis B and Hepatitis C virus | Liver cancer |
Human Papilloma Virus (HPV) | Cervical cancer, Penile cancer, Head and Neck Cancers |
Human Immunodeficiency Virus (HIV) | Kaposi sarcoma, Ca cervix |
Helicobacter pylori | Stomach cancer |
Schistosomiasis | Bladder cancer |
Human T-lymphotropic virus Type I (HTLV-1) | T-cell leukemia and T-cell lymphoma |
The etiology of breast cancer is not fully understood. A variety of interrelated factors can influence its development. These include:
However, in 70% of breast cancer patients no risk factors can be identified.